MitoBreak The mitochondrial DNA breakpoints database
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A human mitochondrial genome database. A compendium of polymorphisms and mutations in human mitochondrial DNA. MITOMAP reports published data on human mitochondrial DNA variation. Currently our variant tables report frequencies from 42616 full length human mitochondrial DNA sequences. Page for details about our new sequence sets.
12081904, POLG, ENSG00000162572, MT-ND1, RCV000000015. A global effort, 100 mitochondrial disease experts.
The group aims at understanding the origin and evolution of genetic diversity, their consequences and applications, both normal and pathological, using autosomal, X and Y linked, and mtDNA markers. In order to achieve the genetic characterisation of normal populations, their origins, phylogeny and evolution, and disease susceptibility profiles, we develop descriptive and analytical formal tools and techniques adequate to specific genomic segments.
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MitoBreak The mitochondrial DNA breakpoints databaseDESCRIPTION
Welcome to the MitoBreak database project. A comprehensive on-line resource with curated datasets of mitochondrial DNA mtDNA rearrangements. MitoBreak provides a complete, quality checked and regularly updated list of breakpoints from. Circular deleted mtDNAs deletions. Circular partially-duplicated mtDNAs duplications. For more background information click here. Or read Damas J, et al. Nucleic Acids Research. 2014. 42 D1 D1261-D1268. What can be found in MitoBreak. 31 short linear breaks.CONTENT
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